Interpersonal communication skills are crucial for building quality interpersonal relationships, mutual respect and trust, and connecting with needs at different levels in health care. Awareness and self-evaluation of one's own communication skills contributes to quality communication, whether it is verbal or non-verbal, as well as different levels of active listening and establishing personal boundaries. Communication in health care is layered and the understanding of all stakeholders is important for achieving quality relationships between health professionals, patients and the patient's family, especially in the area of acceptance of mutual differences in communication patterns. Quality and clear interpersonal communication and the expression of empathy in healthcare can help achieve patient satisfaction and even outcomes, especially in situations where stressors are high. The paper will show the role and importance of interpersonal communication skills with a special emphasis on their self-empowerment in the field of health care through a systematic review of scientific literature. The aim of the work is to show the levels of communication activity through self-evaluation and techniques of self-empowerment of communication skills in addition to a systematic review. The scientific contribution of this thesis is reflected in a more systematic understanding of the importance of self-empowerment of communication skills in health care.