Introduction Belief is a very important force of life. The connection between the body and the spirit and religiosity is an inseparable component of life. Knowing spirituality and the presence of spiritual women help patients and nurses to cope more easily with accepting their disease. Research objective The aim of this research is to show the connection of religious belief with the need for spiritu al care and the way cancer patients cope with their disease. The connection between the relig ious beliefs of nurses, and those who are not, with experiences and their attitudes in relation to the need for spiritual care during the medical care of cancer patients. Subjects and methods The study included 50 cancer patients, 50 nurses working in the palliative care unit and extended treatment of the General hospital and the Homeland War Veterans' hospital Ogulin and the Special hospital for prolonged treatment of Resa's debt. They were investigated through surveys covering 23 issues including age, subject religiosity, connection between religion and disease, impact of religion, prayer and sacraments on disease. The research was conducted in four months. Results It is important for patients to have their religion. Half of the respondents n = 25 (50 %) believe that the religion in God is treating patients. Patients considered to have committed faith n = 19 (90.5 %) confirm that religion in God is helping the disease in relation to nine patients who do not consider this (p < 0,001). 34 (68 %) of patients talk about their disease with their family. Great assistance was also considered as a nurse. Nurses [n = 44 (88 %)] say that religion in God helps in the disease. The Duero also requires the patient to consider a large number of nurses n = 41 (82 %), as well as support for chaplains in the work of nurses n = 28 (56 %). Much more nurses (n = 34) who believe that God and love every man think that the presence of chaplains contributes to facilitating patients’ care compared to five, who do not consider this (p < 0,001). Data on the age of nurses show that siblings aged 40 to 60 years old (n = 28) are struggling to care for dying people. In this way, 13 (46.4 %) are found, whereas young nurses aged 20-39 treat the same work as difficult work (n = three). Conclusion Faith and religious practice significantly contributes to the care of a sick man.Faith also mean s medical nurses. The desire for a permanent priest in the hospital is not only the desire of the patient, but the presence of spiritual women is also necessary for medical nurses to support work and life.