The topic of the thesis is discrimination and stigmatization of patients with mental disorders treated in the hospital. The paper presents the meaning of the biopsychosocial formulation of mental disorders, as well as the concept of stigmatization and discrimination. The aim of the work was to examine the discrimination and stigmatization of patients with mental disorders treated at the Vrapče Psychiatry Clinic in outpatient and day hospital treatment. The Discrimination and Stigmatization Scale (DISC-12) was used, which is a validated instrument for measuring the degree of exposure to discrimination and stigmatization. The respondents were patients with mental disorders treated at the Vrapče Psychiatry Clinic. 93 adults, of both sexes, regardless of age, signed an informed consent and agreed to participate in the anonymous research. Filling in the questionnaire took place from January to June 2024. Three hypotheses were put forward. The first refers to the lived experience of stigma and discrimination in various aspects of functioning in society. The second refers to hiding the illness of people suffering from mental illness, and the third related to gender. It was hypothesized that women experienced more discrimination in finding and keeping a job and accessing education than men. The data analysis confirmed the presence of stigma and discrimination among people suffering from mental disorders in various aspects of functioning in society, as well as the hiding of mental illness, which means that the first two hypotheses have been confirmed. However, the third hypothesis about gender differences in discrimination in finding and keeping a job and access to education was not confirmed because no statistically significant gender differences were observed. Taking into account the research results that indicate the presence of stigmatization and/or self-stigmatization in people with mental illnesses, it is crucial to continuously work on mitigating the negative consequences. It is necessary to implement programs against stigmatization and education of the general population in order to prevent stigma, as the main obstacle to treatment and recovery.