Introduction: The knowledge and opinions of medical nurses and technicians are one of the more important elements in assessing the quality of malignant pain control using multimodal analgesia. Goals: The objectives of this research are to identify and analyze the knowledge and attitudes of nurses/technicians on the suppression of malignant pain using multimodal analgesia with regard to education, years of work experience and position (institute). Respondents and methods: The research was organized as average study (cross-sectional study). The study included 73 nurses/technicians of secondary, higher and high education from three departments of the Clinic for Women's Diseases and Obstetrics (Department of Gynecological Surgery, Department of Gynecological Oncology and Department of Anesthesia and Intensive Care), Clinical Hospital Center Zagreb. Research data were collected using a survey questionnaire taken from B.R. Ferrell and M. McCaffery "Knowledge and attitudes survery regarding pain" abbreviated and translated into Croatian language. Results: According to the set criterion that we consider the result of 60% is good enough, we conclude that nurses/technicians do not have enough knowledge on the suppression of malignant pain using multimodal analgesia. Medical nurses/technicians with higher or high education do not have more knowledge than those with secondary education, and there is no statistically significant difference in relation to different lengths of service. The Department of Gynecological Oncology did not achieve a better result in the study than the Department of Gynecological Surgery and the Department of Anesthesia Intensive Care. Conclusion: Despite the small sample on which the research was conducted, it can be concluded that medical nurses/technicians, regardless of length of service, level of education, or hospital ward where they work, do not have sufficient knowledge to control malignant pain using multimodal analgesia, and there is a need for education in the treatment of pain through lifelong learning programs.