Introduction: Sexually transmitted diseases are among the leading public health problems. Today's pace of life is fast, parents work a lot, teachers are also busy, and the information they get can be inadequate and that can cause wrong attitudes. Young people should be educated early enough, before they form their attitudes, before they have their first sexual intercourse, and before they are exposed to the risk of disease. Objectives: Entrust students with knowledge about sexuality, sexually transmitted diseases, contraception. Methods: Research was conduced on students of the school for nurses from first, third and fifth grade N = 247. An anonymous questionnaire was developed for the purpose of this research. Prior to the research, the permission of the ethics committee and the school principal was obtained. Data was analyzed by statistical methods. Results: Research result found that 32.8% of first, third and fifth grade students are sexually active, most of them are minors, because the average sexual intercourse was at 16 years of age. It should be taken into account that there were more third and fifth grade students than in the first grades, and according to the research, they are also more sexually active. No statistically significant differences were found in the sexual intercourse of male and female students. They are equally sexually active. Students knowledge of sexual and reproductive health is satisfactory because most students knew the correct answers to questions related topic. A statistically significant difference was found only in the question do all sexually transmitted diseases have symptoms. The majority of respondents stated that the introduction of health education in schools would be beneficial. CONCLUSION: As the age increases, so does the number of students who have sexual intercourse. Male students have sexual intercourse a little later, unlike female students. Most students had one or two sexual partners and they believe that they have learned enough through education but they also believe that there is a need to introduce health education in schools. Most students use contraception.