Pain is the oldest medical problem, subject to numerous researches and until now modern medicine doesn't have a reliable tools to objectify and measure it. Each surgical procedure represents the challenge and mobilization of the whole body of the patient, and one of the mechanisms that is activated during and after surgery is the pain mechanism. Thus, pain should be treated as effectively during the procedure and immediately after, to reduce the chances of developing chronic pain from acute postoperative pain. With this study, we wanted to determine whether and to what extent already available questionnaires (PSQ (UBO) and CSQ (PSC)) and the algometre can be used in preoperative stage to estimate the intensity and strength of postoperative pain and to adjust the analgesia protocol. The study was conducted from February to April 2019. at the Clinic for Tumor Clinical Hospital Center Sestre milosrdnice in Zagreb. A study was conducted on 100 female patients aged 30 to 89 who were admitted to the Clinic for breast cancer surgery. Prior to surgery, each participant completed PSQ (UBO) and CSQ (PSC) questionnaires. Prior to surgery pain sensitivity was measured with the algometer which included nine measurements, while the average value of these nine measurements was taken as a reference value in the later study. The same analgesic protocol was applied to all patients included in the study. After the surgery personal pain experience was measured using NRS scales, 2, 6, 12, 18, 24, 48 and 72 hours after the operation. No statistically significant correlation was found between the preoperative pain measurement by alghometer and NRS results from the postoperative period. However, a correlation was found, although not statistically significant, between the PSQ (UBO) and NRS results and a further significant statistical correlation (p <0.05) was found between these two parameters in the patient group defined as a very sensitive (ALG <60 ). Research has shown that using the algometers can identify very sensitive patients and it is possible to plan and adapt the analgesic protocol prior the operation. We can conclude that the results of this study indicate that the analgesic protocol applied during the research was successful in the prevention of postoperative pain. Also, patients more sensitive to pain can be identified by algometric measurements and the PSQ (UBO) questionnaire. The analgesia protocol applied during the research was successful in preventing the occurrence of postoperative pain. However, in patients with high sensitivity the need for additional analgesia could be detected even before the operation by measurements with the algometry or PSQ (UBO) questionnaire.