In this paper, the author, based on the archive material, the press and relevant literature, deals with the topic of the health system and its development in the second Yugoslavia during the first decade after the end of World War II, with main emphasis on the area of Zagreb. After presenting in brief the establishment of new authorities and general political circumstances, the author presents contents of the topic through several thematic chapters, starting with the presentation of the govermnents general health policy and defining its key components and models. Further, a health issue was presented in the city of Zagreb, with particular focus on health policy subjects, ie. the health situation and its solution through the prism of several groups of population: workers, women, children and the elderly. The next section deals with the development of the health service in Zagreb, which includes the institutional and professional aspects of the health system – health center, emergency assistance, field service, hospitals and health care staff. Special chapters are dedicated to informing and shaping the attitudes of the population through the systems of education and propaganda. In the last part of the thesis, a case study was presented on the basis of which functioning of the health system was presented in the example of the fight against tuberculosis in Zagreb.