BACKGROUND: Pediatric palliative care is a special branch of palliative medicine, originating from pediatrics, and means care for seriously ill children from birth to 19 years. In Croatia, there is still no children's hospice in which the child and parents have constant supervision and support, but the organization of palliative care takes place in a hospital or at home. AIM: The aim of this research is to examine the knowledge of nurses about palliative care at the Clinic for Pediatrics of the University Hospital Center Zagreb. METHODS: The study involved 96 nurses employed at the University Hospital Center Zagreb. The research was conducted in the form of a survey consisting of several sociodemographic questions and a PCQN questionnaire. The study was approv the ethics committee of KBC-a Zagreb and informed consent was obtained from each participant. RESULTS: Results are presented by Chi square test, with Fisher correlation for small samples. 99% of respondents are female, and most respondents (41.7%) have 0-5 years of work experience. 39.6% of respondents had 2-7 correct answers, and 60.4% 8-11. No statistically significant difference in knowledge was observed with regard to gender, length of service, professional status and the department in which they work. CONCLUSION: The research tessted objective knowledge about palliative care in KBC Zagreb through a valid questionnaire. According to the obtained results, it is necessary to introduce better education on palliative medicine and to be more focued on overall education to increase the quality of medical care for children.