INTRODUCTION: The corona virus epidemic has become a great public health problem all around the globe. After having the virus isolated and identified, the World Health Organisation has officially named it SARS CoV-2. Because of its fast spreading, and a wide variety of symptoms like headache, sore throat, fatigue, shortness of breath and nausea, corona virus has had a significant impact on the quality of life of those infected. THE OBJECTIVE: Observing the parameters of the quality of life with people infected with COVID, after 6 days of the first sign of symptoms in comparison with the same parameters 28 days after ending the treatment. The hypothesis of the research: female subjects of the research percieve their quality of life in a more negative light than the male subjects. All the subjects of the research claim the quality of their lives has deteriorated in comparison with the time before they got infected. METHODS: The research has been carried out among 100 people, aged 18-80, 6 days after the outbreak of symptoms and 28 days after the end of medical treatment. The location for the experiment was the University Hospital for Infectious Diseases "Dr. Fran Mihaljević", whereas the time span was between 5th February up until the 5th of March 2021. The data was gathered via SF-36 questionaire, used for subjective evaluation of physical fitness and the Barthel index for the objective evaluation of functional abilities. Pain was measured with the help of a Visual Analogue Scale (VAS). IBM SPSS 23 statistical data processing program was used for data processing. As part of the research, the results were presented in descriptive and inferential statistics. The t test for independent samples, the t test on repeated measurements and the Pearson correlation coefficient were used to show statistical differences between the sexes and between the first and second measurements as well as the correlations between the subscales. RESULTS: The results of the research confirmed that most of the patients were aged 61-80, 28 days after overcoming covid the quality of life of the respondents was still impaired. The difference in the quality of life of males and females after COVID was examined, where the results indicated that there was no statistically significant difference between men and women compared to the assessment of current and last year's health (p = 0.15), but women first measurements poorer their current health status compared to last year (M = 55.41; SD = 27.09) compared to men (M = 63.10; SD = 24.53). Despite differences in the mean values of subjective self-assessment of health status between men and women, t tests performed did not show a statistically significant difference on any of the SF-36 subscales. Also, the research obtained results that show that there is a statistically significant difference in all subjects in the quality of life compared to the time before COVID-19 virus (p<0.05). In 17% of subjects after COVID, moderate muscle pain, headache in 30% of subjects, and sore throat in 14% of subjects were still present. Feelings of fatigue during strenuous physical activity remained present in 81% of respondents, and poorer physical fitness after overcoming COVID remained in 64% of respondents. CONCLUSION: Research has shown that the COVID-19 virus has so far had a major impact on the quality of life of patients. In the first and second measurements, a statistically significant difference was recorded in most of the observed parameters, except for the subjective assessment of physical fitness where the performed t tests did not show a statistically significant difference in any of the observed parameters. By providing adequate assistance, the quality of life of the respondents was better after the end of the treatment compared to the arrival at the hospital.